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Plasma TNF concentration was colorimetrically measured using a commercially available enzyme-linked immunosorbent assay (ELISA) kit from R&D Systems (Minneapolis, MN)

(37552484) Risks of high-dose acetylcysteine Case reports describe toxicity (including hemolysis and cerebral edema) following dosing errors resulting in excessive administration of acetylcysteine (e.g., 5-fold increase in the first dose, or 10-fold increase in the maintenance doses)

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