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These observations lend support to the hypothesis that GLP-1/GLP-1R axis might directly act on ovarian MGCs to promote the follicular development in a dose-dependent manner, likely contributing to the oocyte maturation in PCOS
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While GHK-Cu is generally well-tolerated in topical research, certain contraindications or precautions should be considered, especially for systemic research or in specific populations: Systemic Research: For systemic applications, GHK-Cu is generally not recommended for subjects who are pregnant, breastfeeding, have active cancer, or suffer from Wilsons disease (a condition involving copper accumulation)
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For constipation: Add vegetables consistently and increase fluids alongside them
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