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Paired-end FASTQ files were then run through the DADA2 pipeline (v1.8) to generate an amplicon sequence variant (ASV) table and assign taxonomy

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The 50mg intranasal spray formulation provides additional scientific value by allowing laboratories to investigate formulation stability, spray consistency, peptide integrity, copper complex stability, physicochemical characteristics, analytical reproducibility, and intranasal delivery system performance

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Across preclinical studies, Epitalon has shown: Telomerase activation and telomere extension: Via TRAP assays and fibroblast lifespan extension beyond the Hayflick limit Epigenetic remodeling: Reversal of chromatin aging, histone modulation, and gene promoter binding Redox homeostasis: Increased antioxidant enzymes (SOD, NQO1, catalase) and reduced ROS, lipid peroxidation, and DNA damage Circadian restoration: Upregulation of AANAT/pCREB, normalized melatonin and cortisol rhythms, and clock gene modulation in humans Cancer risk reduction: Reduced tumor multiplicity and delayed onset in HER-2/neu and colon cancer models

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