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Patients with pre-existing gastrointestinal conditions including gastroparesis, inflammatory bowel disease, or chronic nauseamay experience more severe side effects with GLP-1 receptor agonists and should discuss these concerns thoroughly with their healthcare provider

Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine , 384, 989-1002

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FDA evaluating three side effects reported with weight loss drugs

doi:10.1001/jama.2023.24539 Seino Y, Fukushima M, Yabe D

If you suspect your fridge dropped below 32F (a power outage, a thermostat malfunction), inspect the vial for cloudiness and floating particles