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A recent study demonstrated that loss of LRRK2 in macrophages led to elevated basal levels of type I interferon and interferon stimulated genes, resulting in an attenuated interferon response to mycobacterial pathogens and cytosolic nucleic acid agonists (Weindel et al., 2020)

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Depending on the seller, purchasers may have limited information about where a substance was manufactured, whether the vial contains the stated ingredient and strength, how it was handled, or whether an injectable product was prepared under appropriate sterile conditions