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Practitioner-reported injectable protocols commonly recommend subcutaneous doses of 250-500 mcg daily in a fasted state, whereas published human studies have evaluated oral doses between 1 and 5 mg daily

Hold the skin taut to prepare the muscle for injection

At the standard escalation of 2.5 mg for 4 weeks then 5 mg, you would use 10 mg in the first month (4 doses at 2.5 mg) and then continue at 5 mg per week

For people with a B12 deficiency, injections are often given weekly for several weeks to restore levels, followed by maintenance doses every 1-3 months

As a result, injectable B12 has become a popular choice for anyone seeking B12 supplementation, not just those with poor digestive health

The Mayo Clinic adds that some people experience side effects with a vitamin injection (9)