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For z-stack and PERMANOVA Data Preprocessing and Imputation: To address missing values in our dataset, we employed a multiple imputation approach using the random forest (RF) method implemented in the mice package (65)

Antioxidant supplementation may marginally increase the success rate

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It modulates dopamine and serotonin turnover in key regions (striatum, frontal cortex, hippocampus), contributing to the observed nootropic and antidepressant effects

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