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Long-term HFD consumption increased hepatic IKK- glutathionylation and NF-B suppression The mechanistic investigations in our cell culture studies provided evidence suggesting that intracellular GSSG accumulation sensitizes hepatocytes to TNF cytotoxicity via the induction of IKK- glutathionylation, leading to reduced IKK- phosphorylation and subsequent NF-B suppression
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Glutathione Antioxidant and anti-inflammatory
The role of gut microbiota in the development of obesity and diabetes (in Eng)
[iv] Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH
The 2.5 mg treatment group experienced a -0.9 kg reduction in body weight
