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Serious but rare side effects include pancreatitis and thyroid concerns

April 24, 2026 Cagrilintide cardiovascular research covering metabolic cardiovascular risk factors, blood pressure effects, and cardiac function in long acting amylin analog research

Lee D et al

These aren't trivial changes

Possible reasons why weight impacts blood pressure include: Visceral fat (fat deep inside the belly) may impair how the kidneys handle sodium and increase sodium reabsorption, contributing to elevated blood pressure

There can be the need for dosing reductions with some medications, such as diabetes and oral contraceptive medications - which is why medical supervision is important