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Melanoma Res 2003
Mechanistically, GLP-1RAs inhibit the activation of hepatic stellate cells (HSCs), which are the principal fibrogenic cell type in the liver
doi: 10.1002/jppr.1897 10
Clinical trials on NAC in IPF have yielded mixed results: some showed slowed lung function decline [155], while a large phase 3 trial found no significant benefit in preserving forced vital capacity (FVC) in patients with mild-to-moderate IPF [156]
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It supports hypertrophy indirectly by elevating growth hormone and IGF-1, improving recovery and protein synthesis
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