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Glucagon-like peptide-1 receptor agonists and risk of neovascular age-related macular degeneration [published online ahead of print June 5, 2025]

Ethanol metabolism, CYP2E1 induction, compromised antioxidant defenses, mitochondrial injury, activation of Kupffer and stellate cells, hypoxia, and iron overload can all contribute to the alcohol-induced oxidative environment

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The tirzepatide dose should remain the same during the switch