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The elevated CHAC1 expression in LUAD promotes tumor proliferation and metastasis by enhancing glycolysis, lactate production, and ATP generation through regulation of pyruvate kinase M2 (PKM2)
Supplements that contain only vitamin B12 tend to contain doses ranging from 500 to 1,000 mcg
Future studies are warranted to determine mRNA and protein levels for these enzymes in tissues of glycine-supplemented fish
M.ParkB
2012 Oct;41(5):309-15
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