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Salicylic acid reduces cadmium (Cd) accumulation in rice ( Oryza sativa L.) by regulating root cell wall composition via nitric oxide signaling
Cancer cells with a hypoxic, chemoresistant, and stemness phenotype have shown sensitivity to DCM, and many analogs are active against multiple drug-resistant cancer cell lines 49,50
(Left) In liver cells, GLP-1 can mediate cholesterol efflux by acting directly on LXR, or by inducing an increase in ATP-binding cassette transporter A1 (ABCA1) mRNA through Ca2+/calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/Prolactin regulatory element binding (CaMKK/CaMKIV/PREB), increasing apolipoprotein AI (apo AI) mRNA and promoter expression, and increasing apo AI secretion, thereby mediating intracellular cholesterol efflux