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(WXYZ) GLP-1 drugs have become powerful tools for weight loss

L-carnitine metabolism to GBB, crotonobetaine, and TMA (and ultimately TMAO) could affect L-carnitine availability for bioenergetics, particularly if biosynthesis is also impaired and/or there is an increased reliance in FAO for energy production (i.e., an increased demand for L-carnitine)

In the clinical trials, those changes were small and temporary, and they shouldnt be an issue for healthy women

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We identified several PCT international patent applications filed in 2023 that have not yet entered into the U.S

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