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She told me she had cried when she first started on Zepbound, so overwhelmed was she to haveafter a lifetime of dieting, dieting, dieting, and regaining the weight anywaya drug that might finally end her health struggles
Heterogeneous results across the trials mean the evidence is suggestive, not conclusive
In a 48-week phase II clinical trial conducted on patients with type 2 diabetes and obesity, treatment with a dose of 10 mg/kg of bimagrumab resulted in a significant reduction in fat mass by 20.5% (compared to 0.5% in the placebo group), while lean body mass increased by 3.6% (as opposed to a decrease of 0.8% in the placebo group), leading to an overall body weight reduction of -6.5%, which was substantially better than the -0.8% observed in the placebo group
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