Given the importance of hyperandrogenism-hyperinsulinemia in PCOS, most of the current therapeutic strategies aim at reducing androgen excess by improving insulin sensitivity, mainly via lifestyle changes and/or pharmacological approaches
Since humans are not able to synthesize vitamins in B complex on their own and these vitamins are easily excreted from the body through urine, their regular intake is essential to maintain energy production, DNA/RNA synthesis/repair, genomic and non-genomic methylation as well as synthesis of numerous neurochemicals and signalling molecules
But here's the frustrating part: maintaining weight loss long-term is where things get tricky
Meijide S, Prez-Ruiz I, Hernndez ML, Navarro R, Ferrando M, Larreategui Z, et al
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