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In middle cerebral artery occlusion (MCAO) models, treatment with exogenous LXA4 provides robust neuroprotection against IRI, markedly decreasing infarct volume and improving neurological outcomes [172, 173]
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The PT is rich in mitochondria since it needs ATP production for reabsorption and transportation against gradients 292,293,294
Serati AR, Motamedi MR, Emami S et al (2010) L-carnitine treatment in patients with mild diastolic heart failure is associated with improvement in diastolic function and symptoms