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Large-scale network dysfunction in major depressive disorder: a meta-analysis of resting-state functional connectivity
Improved insulin sensitivity
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Treatment with DNA methyltransferases (DNMTs) inhibitor 5-aza-2-deoxycytidine (5-Aza) and histone deacetylase (HDAC) inhibitor trichostatin A (TSA) has shown to restore the epigenetically silenced Nrf2 gene and increase NQO1 expression, which helps to prevent prostate cancer progression in TRAMP mice and protects against Alzheimers development in a mouse neuroblastoma N2a cellular model (Yu et al., 2010
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glutathione is needed to help neutralize toxins in the liver
