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For example, EA was conjugated to 2-amino-2-deoxy-d-glucose (EAG) 90 , obtaining an adduct with significant anticancer activity such as EA but without the undesired diuretic activity 90
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Indeed, a randomized controlled trial showed that the combination of EGb 761 with metformin is more effective than metformin alone in improving the outcomes of patients with uncontrolled T2DM ( The GBE therapeutic potential in managing CVDs has not been always clinically observed
10.1124/jpet.116.237503 J
Trends Cell Biol
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