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The authors reported that BPC 157 significantly accelerated the outgrowth of tendon explants and amount-dependently increased the in vitro migration of tendon fibroblasts [2]

Similarly, metabolites such as ferredoxic acid and 2-hydroxyglutaric acid can affect DNA demethylation enzymes (201), thus favoring chromatin condensation and preventing transcription factor binding and gene silencing (202, 203)

Boccia, L

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This happens through the induction of telomerase enzyme activity, resulting in the extension of telomere length

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice