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Due to tirzepatides half-life of approximately five days, its metabolites could potentially be detectable in urine for several weeks (typically 2-4 weeks or more) after the last dose, assuming a sensitive LC-MS/MS method is used

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Arch Med Sci

This is why the bioavailability estimates for sublingual tirzepatide range so widely

Always follow your healthcare providers instructions for the correct usage and consult them for any changes in your dosage.

Protein, resistance training, sleep, and a supervised taper or lower maintenance approach all reduce the chance of regain