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According to research published in the New England Journal of Medicine, patients using Tirzepatide achieved body weight reductions exceeding 20% in some study groups
Retatrutide appears to push the boundaries further with its third receptor target
Therefore, our awareness currently must be on monitoring new drugs which could provide a putative alternative to the current duopoly (as well as drugs that could reinforce the duopoly by resulting in either NVO or LLY or both having an oral alternative)
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The MHRA has licensed several GLP-1 agonists for use in the UK, and NICE guidelines (NG28) recommend them for specific patient groups, particularly those with type 2 diabetes who have not achieved adequate control with other medications or who have additional cardiovascular risk factors
It is important to follow the prescribed doses and directions from your provider accurately in order to minimize risk and/or severity of potential side effects
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