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Similarly, ONCOS-102, an engineered adenovirus expressing GM-CSF, has been tested with pembrolizumab in advanced melanoma (NCT03003676), aiming to activate dendritic cells and potentiate T-cellmediated responses

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Using a collagen gel contraction assay, we observed that primary fibroblasts from the lungs of aged GHK-treated mice exhibited enhanced contraction compared to fibroblasts from placebo-treated mice (Figure 4), further supporting the hypothesis that GHK promotes the resolution of collagen scars