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The closest safety dataset is the Increlex (mecasermin) clinical program , which followed 71 pediatric patients with severe primary IGFD on twice-daily SubQ rhIGF-1 for a mean of 3.9 years (some patients up to 11.5 years)
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Some people fine-tune: e.g., a patient might feel best on 1.7 mg Wegovy and not go to 2.4 because 1.7 mg curbs appetite adequately with tolerable side effects and 2.4 mg adds too much nausea
E.DireitoR.de Alvares GoulartR.et al (2023)
