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J Affect Disord 267:123130

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In patients with T2DM, the pancreas responds initially by expanding the mass of -cells and increasing insulin secretion to compensate for the increased metabolic demand [1]

doi:10.2174/138161211796197179

The core components of the Wnt/-catenin signaling pathway include receptors FZD and LRP5/6, cytoplasmic transducers DvL, AXIN, APC, GSK-3, and CK-1, the key effector -catenin, and the transcription factor TCF/LEF (Foord et al., 2005