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Obesity has impacts on cardiovascular disease outcomes through increased risk of coronary artery disease, heart failure (more prominent with preserved ejection fraction), cardiac arrhythmias (most significantly atrial fibrillation), sudden death, and venous thromboembolism [7]
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Lowering costs can be achieved through innovative manufacturing techniques, economies of scale, and streamlined regulatory pathways [36,37,38]
3,4 Another agent gaining in popularity is tirzepatide (Mounjaro, Zepbound), a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RA
Diabetologia 55(9):24562468 Lee YS, Jun HS (2016) Anti-inflammatory effects of GLP-1-based therapies beyond glucose control
However, clinical studies revealed an additional benefitsignificant weight loss
