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NGS Genetic Testing can be a powerful tool in diagnosing this rare genetic disorder, and can help to guide treatment decisions and improve outcomes

Singleton, J

Anti-inflammantory and antioxidant effects of vitamin A (212, 213), C (214, 215), D (216, 217) and E (213) also involve inhibition of NF-kB as well as activation of Nrf-2 signaling pathways involved in cellular antioxidant response (218, 219)

This manifests as AKI, requiring renal replacement therapy in severe cases and significantly increasing mortality risk ( Cardiac injury: Myocardial IR during cardiac surgery generates substantial mtDAMPs release, contributing to post-cardiotomy syndrome (fever, leukocytosis, organ dysfunction) and low cardiac output syndrome

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