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A: Gastrointestinal discomfort stands as the dominant adverse response of GLP-1 agonists, including mild nausea, transient vomiting, bloating, diarrhea or constipation, which mostly emerge within the initial 28 weeks of administration as the gastrointestinal tract adapts to delayed emptying effects
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Morton, G
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The most commonly cited starting protocol in the medical literature and clinical practice involves 250 micrograms administered once daily for acute injury, stepping up to 500 micrograms daily if response is insufficient after one to two weeks
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