Takeaway GLP-1 is a naturally occurring hormone in the human body that regulates blood sugar levels as well as reduces appetite to control body weight
Compounded GLP-1 medications are prepared by licensed 503A compounding pharmacies based on individual patient prescriptions
Real-world comparison of oral versus injectable semaglutide Fadini et al
Your doctor can help you evaluate whether compounded options are appropriate for your situation and how they compare to brand-name medications
The GLP-1 component has been studied for incretin-pathway signaling, including effects on insulin secretion and satiety-related neural circuits in animal models
Trade group Outsourcing Facilities Association hit back with a lawsuit, calling the FDAs move arbitrary and one that lacked any semblance of lawful process. Ultimately, however, following a months-long review, the FDA doubled down on its original declaration, announcing in December 2024 that tirzepatide is no longer in shortage