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Within this framework, selection biomarkers are particularly important

Grether-Beck S, Mhlberg K, Brenden H, Felsner I, Brynjolfsdottir A, Einarsson S, Krutmann J (2008) Bioactive molecules from the Blue Lagoon: in vitro and in vivo assessment of silica mud and microalgae extracts for their effects on skin barrier function and prevention of skin ageing

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The chemokine CCL2 mediates migration that increased BBB permeability, as shown when HIV-1 infected lymphocytes were added to transwells with astrocytes and BECs (Eugenin et al., Cancer Cells Malignant glioma cells infiltrate peri-vascular spaces and displace astrocytic end-feet from BECs (Cuddapah et al., 2014)

S., Navani, R., Navani, A., da Fonseca, L