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However, in people with type 2 diabetes, GIP does not contribute at all to the total insulin secretion effect of the combination while the insulinotropic effect of GLP-1 is only slightly impaired
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& Fernandez-Checa, J
BAT: tejido adiposo marrn
Research has shown that variations in the OCT1 gene play a significant role in the varying effectiveness of metformin treatment for individuals with T2DM (Gambineri et al., 2010
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