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Gordon Williams at Brigham and Womans Hospital, Harvard Medical School, Division of Endocrinology, Diabetes and Hypertension, for sharing their salt sensitivity data that appear in Fig

Research has demonstrated its involvement in wound healing through enhanced collagen and decorin gene expression [1] , activation of tissue remodeling pathways [2] , and regulation of genes associated with antioxidant defense and anti-inflammatory responses [3] [4]

Each experiment was conducted independently three times with duplicate measurements to ensure reproducibility and statistical robustness [1]

Consequently, it contributes to addressing various cosmetic skin concerns, such as wrinkles, fine lines, dry skin, saggy skin, and dark spots

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Monomers fold into a two-domain configuration to form the active enzyme structure