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Finally, heterogeneity in ascent profiles, altitude reached, duration of exposure, and supplementation protocols, quantified by the I 2 statistic and addressed using a random-effects model, may have contributed to variability across studies and constrained further stratified or sensitivity analyses

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Effects of the glucagon-like peptide-1 receptor agonist liraglutide on 24-h ambulatory blood pressure in patients with type 2 diabetes and stable coronary artery disease: a randomized, double-blind, placebo-controlled, crossover study

This observation emphasizes not only the importance of proper treatment timing but also offers critical insights for clinical practice

The details can vary by medication, procedure, health history, and individual treatment plan