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By bypassing the digestive system, ingredients like berberine, green tea extract, and B vitamins are said to absorb steadily through the skin

11 Amorim Moreira Alves, G., Teranishi, M., Teixeira de Castro Gonalves Ortega, A

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2 In addition to lifestyle modifications (diet and exercise), many pharmacologic strategies have been proposed to counter iatrogenic weight gain, including appetite suppressants (eg, pro-dopaminergic agents such as phentermine, stimulants, and amantadine), pro-anorectant anticonvulsants (eg, topiramate or zonisamide), opioid receptor antagonists (eg, olanzapine/samidorphan or naltrexone) and oral hypoglycemics such as metformin