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In ALS, GLP-1 analogues have extended survival in preclinical studies
Additionally, many patients abandon GLP-1 medications due to intolerable side effects, including nausea, vomiting, diarrhea, and fatigue
doi: 10.1186/1550-2783-2-2-38
These are often nutritional in origin and can frequently be addressed through diet or supplementation
Mondelez International, which produces packaged food products, has seen its stock price fall as comments from Walmart indicated that individuals taking GLP-1 drugs have reduced the amount of food they purchase
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Specifically, PS-NPs have been shown to decrease cell viability and mitochondrial membrane potential in the human ovarian granulosa cell line COV434, increase the expression of apoptosis- and oxidative stressrelated markers, and induce cell cycle arrest [30]
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