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It can also be mental/emotional, as well as physical

A recent study suggests it may also help with rheumatoid arthritis

New and existing patients are eligible

Image z-stacks were collected with a step-size of 1 m and rendered as three-dimensional rotational animations using Imaris 8.1.2 software (Supplementary videos 1 and 2)

Limitations include relatively short treatment periods (6 weeks per arm), potential carryover effects despite washout, modest sample size limiting power for subgroup analyses and exclusion of newer agents (e.g., tapentadol) and long-term safety outcomes, which may restrict applicability to broader clinical practice

10.1016/j.alcohol.2017.02.357 88 ManzardoA