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Patients should follow specific storage instructions provided with their medication and never freeze or expose peptides to extreme temperatures

Medicines for obesity work best when they are combined with healthy eating, physical activity, sleep support, and long-term behavior change

The SELECT trial (Lincoff et al., N Engl J Med, 2023) demonstrated a 20% reduction in major adverse cardiovascular events with semaglutide 2.4 mg in overweight/obese patients with established cardiovascular disease

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As mentioned earlier, the most important effect of incretins is to stimulate the production and secretion of insulin by the pancreas, and clinical studies show that the activation of this process, whether by stimulation of GLP-1 by semaglutide alone or simultaneous stimulation of GLP-1/GIP by tirzepatide, is associated with better glycemic control in type 2 diabetics

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