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Notably, although the extent of weight loss is reduced in both CNS GLP-1R KO and CNS GIPR KO mice treated with mGIPR-Ab/GLP-1, it is not completely abolished, suggesting that each receptor contributes to the weight loss observed in control mGIPR-Ab/GLP-1-treated mice

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Terzepatide, an investigational medication thats on late-stage FDA approval (LINK), combines the actions of GLP-1 agonists and glucose-dependent insulinotropic polypeptide receptor agonists (GIP agonists)

Remember the effects of semaglutide wear off within weeks

Another alternative is copper peptide tablets