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GLP-1 medications produce significant weight loss in clinical trials, with average results ranging from 15 to 22 percent of body weight depending on the medication and dose

GLP-1 receptor agonists slow gastric emptying, meaning food remains in the stomach longer before moving into the small intestine

The observed 18.6- and 20.9 pmol/l rise in circulating plasma PYY levels at 30 and 60 min is in line with previous studies which administered a mixture of SCFAs

Most users see brighter tone between weeks 8 and 12

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An active-comparator new-user cohort design [31, 32] compares initiators of different active treatments by emulating an active-controlled randomized trial