Similar effects were observed with neural stem cell or bone marrow stromal cell injections
Arosio E, De Marchi S, Zannoni M, et al
A study by Naziroglu et al
ATP emit energy signals, ATP-P2RY2 binding is involved in the recruitment of monocytes or macrophages, neutrophils, and promoting DC maturation (19)
Alternatively, preclinical studies using leptin-deficient animals ( ob/ob mice) demonstrated that restoring plasma leptin concentration to normal improved heart function after MI, and that these beneficial effects were associated with reductions in cardiac inflammation and apoptosis [13, 14] and activation of anti-hypertrophic pathways in obese animals with left ventricle (LV) hypertrophy [8]
Each improvement in protocol execution translates to better results per dollar spent