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Finally, riboflavin deficiency may be reversible through dietary supplementation and adequate ingestion of this vitamin, which may prevent neurological disorders, such as migraine, besides depression (, , )
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However, such a decline in serum B12 among elderly adults is not consistent (Vogiatzoglou et al., 2009
Thrombocytosis: Dangerous Increase in Blood Platelets B12 replacement therapy can trigger significant thrombocytosis (excessive production of platelets, the blood cells responsible for clotting)
In a post hoc analysis after 13 years of the study, a 13% increased risk of vitamin B12 deficiency per year of metformin use was reported (Aroda et al, 2016)
