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They wrote in Annals of Internal Medicine that first-line treatments for obesity and overweight include physical activity and nutrition, but the new guidance addresses additional management using pharmacologic treatments when lifestyle modifications alone do not result in optimal weight loss or weight maintenance for a person. ACPs recommendations also come as other professional medical societies and organizations, including WHO, The Obesity Society and Obesity Medicine Association, have announced their support of medications like GLP-1 receptor agonists for obesity

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Its important to be aware of these before starting either medication, whether used alone or in combination