One case report utilized KD (65% fat, 25% protein, 10% carbs) with a time-restricted feeding window in a 65-year-old woman with major depression and type II diabetes and reported remission of depression (PHQ-9 17 to 0), normalization of HbA1c, decrease in estimated average glucose from 216 to 96 mg/dL, improvement in HOMA-IR from 9.4 to 2.3, and TG/HDL ratio from 4.7 to 1.2 over 12 weeks
J.ChengY.LiW.DongX
Further reading Retatrutide lowers blood sugar and weight in people with type 2 diabetes mellitus Eli Lillys triple agonist retatrutide demonstrated significant reductions in HbA1C and weight when used as an adjunct to diet and exercise, according to topline results from a phase III TRANSCEND-T2D-1 trial
However, in autoimmune diseases like psoriasis, the immune system mistakenly attacks the bodys own cells
This has been demonstrated for SIRT1 and, more recently, for SIRT2 (Guarente, 2013
By binding to GLP-1 receptors in the brain's hypothalamus, semaglutide reduces appetite, slows gastric emptying, and improves insulin sensitivity -- three mechanisms that together produce sustained caloric reduction without the hunger spikes that sabotage traditional diets