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In 2024, Novo Nordisk was removed from the FDA drug shortage list for certain semaglutide presentations, which triggered debate about whether 503A compounding of the molecule would remain permissible [6]

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This raises the risk of falls, especially among older adults

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Final approval: FDA issues a formal decision

This is accomplished in the Pyruvate dehydrogenase complex (PDC) which is a complex of three enzymes that transform pyruvate into acetyl-CoA through a process called pyruvate decarboxylation