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doi: 10.2337/dbi21-0004 64 FriasJPDaviesMJRosenstockJPerez ManghiFCFernandez LandoLBergmanBKet al

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This was examined by assessing associations between frequency of polymorphisms in key metabolism enzyme genes and latitude, with findings unsupportive of this hypothesis but suggesting that folate genotypes are selected to maintain homeostasis within the folate system

Immune response