The enzyme jasmonoyl isoleucine conjugate synthase 1 (JAR1) in the cytosol catalyses the final step, although at least one alternative enzyme to JAR1, designated GH3.10, is present in leaf tissue (but 12hydroxy-jasmonic acid is its preferred substrate)
It is particularly effective when taken in conjunction with sports, as it increases fat burning during exercise
It slows down how quickly your stomach empties, which keeps you feeling full longer, and it acts on your brain to reduce appetite and cravings
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J Biol Chem 276:1274912755