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Semaglutide investigation for metabolic research models in teenagers: a plain language [PMID: 36534451] Laboratory literature summary: Semaglutide investigation for metabolic research models in teenagers: a plain language summary of the STEP TEENS research study
[19] Ren J, Hao Y, Liu Z, Li S, Wang C, Wang B, et al
10.1021/pr101004j 166 ZelenakC.EberhardM.JilaniK.QadriS
Although current evidence supports broad applicability across BMI, diabetes status, and fibrosis stages F2-F3, subgroup analyses suggest attenuated responses in non-obese patients and in certain ethnic groups (Hispanic patients in ESSENCE), emphasizing the need for precision medicine approaches incorporating anthropometric, genetic (e.g., PNPLA3, HSD17B13), and metabolic profiling