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Orphanet Journal of Rare Diseases

To quantify glutathione in both the oxidized and reduced forms, the GSH/GSSG-Glo Assay uses two reaction configurations to independently quantify GSH and GSSG (Figure 1)

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Optic Nerve Atrophy: Administering cyanocobalamin to patients with Leber's disease or hereditary optic nerve atrophy should be done cautiously, as it may worsen the condition

Diverticular disease has been noted in patients with clEDS (6/31 patients in the literature) and in our cohort two patients (P6, P17 [terminal ileum, colon]) had proven and one suspected colonic diverticulosis