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Jakubowski and collaborators have recently reported that cells efficiently convert homocysteine into homocysteine thiolactone by methionyl-tRNA synthetase (Jakubowski et al, 2000b)
The Midpoint Cohort is ongoing, with 6-month randomized data expected in Q1 2026
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Accordingly, the participant was included in the safety analysis set but excluded from the efficacy and PK analysis sets
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Additionally, exosomes from miR-486-modified dental pulp stem cells exhibited better inflammatory regulation in high-altitude pulmonary edema animal models (Wang et al., 2025)
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