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The FDA's pediatric drug development guidance specifically requires dedicated pediatric pharmacokinetic studies before dosing recommendations can be made for new molecular entities in patients under 18 [16]

Following standardized preparation procedures helps improve the reliability and reproducibility of laboratory research

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Indeed, it is evident that high concentrations of Vitamin B12 are an essential component of a healthy and active lifestyle

Store the medication in a dark place, as it's light-sensitive, and keep it out of reach of children

Concurrent medications (metformin, PPIs, antibiotics) and underlying gastrointestinal conditions may cause diarrhoea coinciding with B12 supplementation